منابع مشابه
Turn-ons for axons
In This Issue In This Issue Nuclear proteins get around rotein trafficking between the cytoplasm and the nucleus has been studied extensively; but how do proteins move from one site to another within the nu-cleus? On page 615, Leung and Lamond focus on the intranuclear trafficking of the RNA-binding protein NHPX, and describe an elegant series of experiments that demonstrates the existence of m...
متن کاملChromatin turn ons and turn offs of ribosomal RNA genes.
Eukaryotes have hundreds (sometimes thousands) of ribosomal RNA (rRNA) genes whose transcription by RNA polymerase I helps establish the proliferative ability of cells by dictating the pace of ribosome production and protein synthesis. Interestingly, only a subset of the total rRNA gene pool is active at any one time, making rRNA genes attractive for understanding the dynamic balance between ge...
متن کاملMixing Signals: Molecular Turn Ons and Turn Offs for Innate γδ T-Cells
Lymphocytes of the gamma delta (γδ) T-cell lineage are evolutionary conserved and although they express rearranged antigen-specific receptors, a large proportion respond as innate effectors. γδ T-cells are poised to combat infection by responding rapidly to cytokine stimuli similar to innate lymphoid cells. This potential to initiate strong inflammatory responses necessitates that inhibitory si...
متن کاملAxons Turn as Netrins Find Their Receptor
underscored in the netrin-1 knockout mouse, whose The idea of chemoattraction as a guiding mechanism major forebrain commissures, the corpus callosum, hipfor growing axons was originally suggested by Ramon pocampal and anterior commissures, are completely y Cajal as a result of earlier work on leucocytes. Disabsent. The additional absence of pontine nuclei raises cussing the ventral navigation ...
متن کاملPut-Offs and Come-Ons
The front cover describes the subject of the book as the manoeuvres and stratagems by which men, women and children deceive, compete , conflict, manipulate, make love and annihilate each other.
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2002
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1574iti1